Reasons/Comments Absorica (isotretinoin) Capsule Mucous membrane irritant: Accutane (isotretinoin) Capsule: Mucous membrane irritant AcipHex (rabeprazole) Tablet Slow-release Procardia XL ( NIFE dipine) Tablet Slow-release Kapidex (dexlansoprazole) Capsule Slow-release (a) (Note: name changed to Dexilant), Kapvay (clo NID ine) Tablet Slow-release Hzr``bdx c`@ b Ecotrin Maximum Strength (aspirin) Tablet Enteric-coated Rockville, MD 20857 endstream endobj startxref Viramune XR (nevirapine) Tablet Slow-release (b) 1 Course Definition and Alignment Table Tania Woolfolk Capella University NURS-FPX6111 Prof Marylee Bressie February 8, Fig 2.7 Medication discrepancies at various transitions of care. This bulletin presents ISMP's analysis and decision to reaffirm the Do Not Use: Dangerous Abbreviations, Symbols and Dose Designations List. Evista (raloxifene) Tablet Taste; teratogenic potential (i) What price must we pay for safety? The List of Oral Dosage Forms That Should Not Be Crushedwas originally compiled and updated by John Mitchell, PharmD. Two official USP terms are used to designate special-release medication forms : "extended release" and "delayed release." Others (e., sustained release, controlled Nifedical XL ( NIFE dipine) Tablet Slow-release Over 30 drug products based on these technologies have been approved by the Food and Drug Administration, and more are in the development pipeline. Mitchell JF; Institute for Safe Medications Practices; ISMP. %PDF-1.6 % Pancrelipase ------ Capsule Enteric-coated (a) Annual Perspective: Topics in Medication Safety. To ensure that certain medications are used safely, this updated list includes oral medications that should not be crushed and specifies why. 5200 Butler Pike Exploring pharmacist experiences of delivering individualised prescribing error feedback in an acute hospital setting. HHS Vulnerability Disclosure, Help Developed in 2020 to help healthcare facilities standardize smart infusion pump technology. Evaluating the implementation and impact of a pharmacy technician-supported medicines administration service designed to reduce omitted doses in hospitals: a qualitative study. Valcyte (val GANC iclovir) Tablet Teratogenic and irritant potential (i, b) The site is secure. Plymouth Meeting, PA 19462. Afeditab CR (NIFEdipine) Tablet Slow-release Our error reporting program, education, and advocacy have helped protect millions of patients. NurseyPoo7 275 Posts Specializes in Acute Care. TheList of Oral Dosage Forms That Should Not Be Crushed,commonly referred to as the "Do Not Crush" list, contains medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. Key Words: - Error-prone acronyms - Symbols - Dose designations - Transitions of care - Individual Practitioner Reporting (IPR) - Community Pharmacy Incident Reporting (CPhIR) - Consumer Reporting Oct 9, 2008 h $ 6&Fdk~0 & B tablets can cause rapid release and absorption of a (d) Capsule may be opened and the liquid contents removed for administration. 5200 Butler Pike Enablex (darifenacin) Tablet Slow-release Entocort EC (budesonide) Capsule Enteric-coated (a) Hydrea (hydroxyurea) Capsule Note: exposure to the powder may cause serious skin Unauthorized use of these marks is strictly prohibited. Doxidan (bisacodyl) Tablet Enteric-coated (c) Temodar (temozolomide) Capsule Slow-release (Note: accidentally opened or damaged February 12, 2021. Propecia (finasteride) Tablet Note: women who are, or may become, pregnant, tablets may result in overdose or death), Oracea (doxycycline) Capsule Slow-release This chart, commonly referred to as the "Do Not Crush" list, alerts healthcare professionals about medications that should not be crushed because of their special pharmaceutical formulations or characteristics, such as oral dosage forms that are sustained-release in nature. 2021 Feb 19;78(5):389-394. doi: 10.1093/ajhp/zxaa412. hb```f`` Ab@ $*'DE4rmK[>53I69hz0av] {GNXv,`30 |1;[?tVmB !f 915d5 Hl All rights reserved. 114 0 obj <>/Encrypt 92 0 R/Filter/FlateDecode/ID[<9C316512FA01DB64926B07496F4C98EF><2051BE4FD64FB74C8C9DFE3DFF6A8BC1>]/Index[91 40]/Info 90 0 R/Length 105/Prev 229382/Root 93 0 R/Size 131/Type/XRef/W[1 2 1]>>stream Detrol LA (tolterodine) Capsule Slow-release 2023 Institute for Safe Medication Practices. Theo-24 (theophylline) Capsule Slow-release (Note: contains beads that dissolve hbbd``b`@1$X BH$D b\ ma@`24 MeSH Ecotrin Adult Low Strength (aspirin) Tablet Enteric-coated Use of complete medication history to identify and correct transitions-of-care medication errors at psychiatric hospital admission. In: StatPearls [Internet]. ISMP has discontinued the sale of wall charts. may generally be administered via nasogastric tube using an appropriate fluid provided entire contents are washed down the tube. Xarelto (rivaroxaban) Tablet Note: crushed tablet must be given within 4 hours. This wall chart includes both generic/brand names, identification of first line ACLS drugs, mechanism of actions and uses, dosage/administration, adverse drug reactions, contraindications and special considerations for medications supplied in crash carts. contact; health care workers should take appropriate And if you do choose to submit as a logged-in user, your name will not be publicly associated with the case. Oxy CONTIN (oxy CODONE ) Tablet Slow-release (Note: tablet disruption may cause a Effervescent Potassium ------ Tablet Effervescent tablet (f) Policy, U.S. Department of Health & Human Services. Professor Parsons, Lesson 8 Faults, Plate Boundaries, and Earthquakes, General Chemistry I - Chapter 1 and 2 Notes, Chapter 3 - Summary Give Me Liberty! Analyze your current status with implementation. official website and that any information you provide is encrypted ISMP has discontinued the sale of wall charts. Invega (paliperidone) Tablet Slow-release Such manipulations can compromise the integrity of the formulation and subsequently alter the oral bioavailability. Electronic Top 10 Medication Errors and Hazards that appeared in the ISMP Medication Safety Alert! Copyright by International Journal of Pharmaceutical Compounding, Inc. sharing sensitive information, make sure youre on a federal capsules; all women should use caution in handling Erivedge (vismodegib) Capsule Note: package insert indicates potential teratogenic requires the patient to slowly allow dissolution) (a) Capsule may be opened and the contents taken without crushing or chewing; soft food such as applesauce or pudding may facilitate administration; contents Tecfidera (dimethyl fumarate) Capsule Slow-release Miller D, Miller H. To crush or not to crush? Oral Dosage Forms That Should Not Be Crushed 2022 28" X 40" (width X height) Ships in a tube. The https:// ensures that you are connecting to the An official website of the United States government. VoSpire ER (albuterol) Tablet Slow-release Tracleer (bosentan) Tablet Note: women who are, or may become, pregnant, Permission is granted to reporduce material for internal use within healthcare organizations. Strategy, Plain FOIA 4836 0 obj <>/Filter/FlateDecode/ID[<262A6F7D26F5DF4CB425F5679D3D8F83>]/Index[4817 33]/Info 4816 0 R/Length 95/Prev 354504/Root 4818 0 R/Size 4850/Type/XRef/W[1 2 1]>>stream tablets can cause rapid release and absorption of a Commonly referred to as the "Do Not Crush" list, healthcare professionals are alerted about medications that should not be crushed. Disclaimer: ISMP does not own, update, or review new or existing content on the List of Oral Dosage Forms That Should Not Be Crushed. Styrofoam or plastic materials Drug-Rich Phases Induced by Amorphous Solid Dispersion: Arbitrary or Intentional Goal in Oral Drug Delivery. What to consider before giving medications to a . Recent pharmaceutics innovations such as nanocrystals and amorphous solid dispersions have been used successfully to improve oral bioavailability of drugs. Prevacid SoluTab (lansoprazole) Tablet Note: orally disintegrating do not swallow; dissolve in Recent Advances in Solid Dispersion Technology for Efficient Delivery of Poorly Water-Soluble Drugs. Medications requiring special safeguards to reduce the risk of errors and minimize harm. Report an Error Medication Safety Highlights Featured Articles water only and dispense via dosing syringe of NG tube, Prevacid Suspension (lansoprazole) Suspension Slow-release (Note: contains enteric-coated granules; Here is a list of non-crushable meds: http://www.ismp.org/Tools/DoNotCrush.pdf It's pretty extensive. throughout the GI tract) The problem with medication reconciliation. 2021 Feb 19;78 (5):389-394. doi: 10.1093/ajhp/zxaa412. Prevacid (lansoprazole) Capsule Slow-release Janumet XR (combination) Tablet Slow-release Droxia (hydroxyurea) Capsule Note: exposure to the powder may cause serious skin 2021 Sep-Oct;25(5):364-371. Ditropan XL (oxybutynin) Tablet Slow-release Identify patient safety risks with web-based surveys and dashboards. And if you do choose to submit as a logged-in user, your name will not be publicly associated with the case. Ergomar (ergotamine) Tablet Sublingual form (g) Khedezla (desvenlafaxine) Tablet Slow-release Pleaseclick hereto purchase theOral Dosage Forms That Should Not Be Crushed WallChart from Thomas Land Publishers. Document number: 010-03-09-004 Review date: April 2021 Developed and maintained by Bernadette Rehman, Clinical Pharmacist, Residential Aged Care, Waitemata District Health Board, New Zealand and . Q: There used to be a Do Not Crush List in table form on ISMPs website. ISMP offers a wide range of downloadableand easy to use resources. 2023 Institute for Safe Medication Practices. Identify best practices to support safe use of technology and automation in sterile compounding. Do Not Crush Drugs Certain medications have a special release mechanism designed to slowly release a certain amount of medication over a given amount of time. Electronic Bisacodyl (combination) Tablet Enteric-coated (c) potentially fatal overdose of oxy CODONE), Pancreaze (pancrelipase) Capsule Enteric-coated (a) endstream endobj 4818 0 obj <. Oral Dosage Forms that Should Not Be Crushed. Consensus-based best practices for issues that continue to cause fatal and harmful errors. View NURS_FPX 6111_Assessment 1_2 (1).docx from MSN 6111 at Capella University. Bisa-Lax (combination) Tablet Enteric-coated (c) Lescol XL (fluvastatin) Tablet Slow-release The term "Slow-release" is being used here to signify all such drugs with a special-release mechanism. Keppra XR (lev ETIRA cetam) Tablet Slow-release (b) ASHP national survey of pharmacy practice in hospital settings: prescribing and transcribing2013. Dilatrate-SR (isosorbide) Capsule Slow-release 2021, Thomas Land Publishers, Inc. Please select your preferred way to submit a case. Figure 2.7 [12] is an image from the World Health Organization showing ranges of percentage of errors that occur during common transitions of care. Bethesda, MD 20894, Web Policies ISMP has discontinued the sale of wall charts. Understanding and managing IV container overfill. Nucynta ER (tapentadole) Tablet Slow-release (Note: crushing, chewing, or dissolving Noxafil (posaconazole) Tablet Slow-release (b) Int J Pharm. Qian K, Stella L, Jones DS, Andrews GP, Du H, Tian Y. Pharmaceutics. Voltaren XR (diclofenac) Tablet Slow-release The ISMP Do Not Crush List was reviewed, and the products in question were identified if they were listed with "no reason" provided or "film-coated" as the only reason. Easprin (aspirin) Tablet Enteric-coated Top 10 Medication Errors and Hazards that appeared in the ISMP Medication Safety Alert! 5-10 In addition, the table lists the products' status on the ISMP Do Not Crush List and alternative dosage forms (if available). Treasure Island (FL): StatPearls Publishing; 2022 Jan. Mitchell JF; Institute for Safe Medications Practices; ISMP. We encourage ISMP to add these drug products to the Do Not Crush list due to wide use of this list throughout healthcare. Klor-Con M (potassium) Tablet Slow-release (b,h) Kaletra (combination) Tablet Film-coated In the meantime, pharmacists should be mindful of the new formulation technologies and advocate for the proper use of these drug products. Indocin SR (indomethacin) Capsule Slow-release (a,b) Biltricide (praziquantel) Tablet Taste (h) Trilipix (fenofibric acid) Capsule Slow-release Filling the gaps on the Institute for Safe Medication Practices (ISMP) Do Not Crush List for Immediate-release Products. Learn more information here. Please click here to purchase the List of Oral Dosage Forms That Should Not Be Crushed Wall Chart from Thomas Land Publishers. Rapamune (sirolimus) Tablet Note: pharmacokinetic parameters may be affected Medications that should not be crushed because of their special pharmaceutical formulations or characteristics. Utilization of pharmacy technicians to increase the accuracy of patient medication histories obtained in the emergency department. Institute for Safe MedicationPractices The .gov means its official. Biohist LA (combination) Tablet Slow-release (h) Erythromycin Delayed-Release ------ Capsule Enteric-coated pellets (a) Exjade deferasirox Tablet Note: do not give as tablet; tablets are meant to be given as a liquid; see company insert. Sular (nisoldipine) Tablet Slow-release Doxy-50 Do not crush; contents are irritant to mucous membranes and may cause oesophageal ulceration if crushed. - Do not crush (risk of sensitization, and taste is unacceptable for oral administration) cinacalcet Sensipar Tablet Note: tablets are not scored and cutting may cause variable dosage accuracy cloNIDine Kapvay Tablet Slow-release - Do not crush sustained-release product - Immediate-release tablet may disperse ISMP has discontinued the sale of wall charts. %%EOF to apple juice or applesauce but NOT chocolate), Cytovene (ganciclovir) Capsule Skin irritant Norvir (ritonavir) Tablet Note: crushing tablets has resulted in decreased The authors provide recommendations for clinicians to aid in clinical decision-making regarding crushing, such as suitable personal protective equipment and prompt administration. Summary: Sites, Contact potentially fatal dose) Medication safety in the emergency department: a study of serious medication errors reported by 101 hospitals from 2011 to 2020. DynaCirc CR (isradipine) Tablet Slow-release, E.E. The list is now maintained and updated by Thomas Land Publishers. Rockville, MD 20857 Resource Location: http://www.ismp.org/tools/donotcrush.pdf. Medication errors can occur during these changes in settings. Please select your preferred way to submit a case. EC-Naprosyn (combination) Tablet Enteric-coated December 22, 2021. 2022 Oct 9. potentially fatal overdose of drug) Intuniv (guan FACINE ) Tablet Slow-release American Society of Health-System Pharmacists 2020. Acute hospital setting are used safely, this updated list includes Oral medications that Should Not crushed. ; 78 ( 5 ):389-394. doi: 10.1093/ajhp/zxaa412 the tube nasogastric tube an. 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Associated with the case ( a ) Annual Perspective: Topics in Medication Safety, E.E: There used be. Healthcare facilities standardize smart infusion pump technology official website of the formulation subsequently!

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